A new study published in the British Medical Journal proves how coffee consumption affects the human body and prevents the development of prostate cancer in men.
The research was a result of a cohort study conducted by meta-analyses and systematic review of the previously available data in this regard.
Drinking several cups of coffee every day may be linked to a lower risk of developing prostate cancer, suggests a pooled data analysis of the available evidence, published in @BMJ_Open https://t.co/g8Er1DheFt
— BMJ (@bmj_company) January 12, 2021
Coffee has been studied for a decade on its affects in the human body. It is quite known for the prevention of various types of cancers. Coffee contains diterpenes of kahweol acetate, cafestol and other antioxidants. These constituents have a potential to inhibit the proliferation of cancerous cells including the tumors present in the prostate.
Prostate cancer is usually developed at the adenocarcinomas level. The cells in the glandular part of the prostate undergo abnormal mutations. This results in the spread and multiplication of the tissues in the prostate gland causing deleterious effects.
Prostate cancer is the second most frequently diagnosed cancer in the world and the sixth leading cause of death in men due to cancer. The prevalence of this cancer stresses on the strategies to prevent prostate cancer.
The study was conducted in the countries where the people are used to drinking lots of coffee. People in the US, Canada, Sweden and Japan were analyzed how the use of coffee has implied its effects on decreasing the risk of prostate cancer in adult men. The study collected the data on how the frequency of the consumption of coffee per day.
The units used were the number of cups used per day or the number of ml consumed on a daily or weekly basis. The highest and lowest levels of coffee consumption were found to vary in different groups of people. The measure of prostate cancer and the staging and grading of this cancer in men was obtained using the physician and clinical records.
Localized and non-aggressive prostate cancers were analyzed separately as well. Participants of the study were grouped into the ones who had either lethal or curable cancer to assess the effect of coffee consumption on them.
The analyses were conducted by including the prostate-specific antigen (PGA) results taken from the participants of this research. The analyses of the family history on prostate cancer, drug use, alcohol consumption, weight of the participants and their other lifestyle patterns. The analysis was done in detail by pooling the results obtained from each data and performing a meta-analysis approach.
A total of 497 records were obtained from three databases. Out of these only 280 remained after proper screening. The observations and data were also included from the previous studies so as to expand the data for authenticity.
It was reported that only 15 participants gave a record of the effect on the prevention of prostate cancer when the coffee consumption varied from lower to higher levels. An idea was interpreted by the data submitted by 13 participants on how the risk was associated with an increase of one cup of coffee per day. This was sufficient to estimate the dose response of coffee constituents on the prevention of prostate cancer.
It was concluded that there was a 7% reduction in the risk of prostate cancer in the group which consumed the highest levels of coffee per day. It is an interesting fact that coffee can be used to lessen the risks of this cancer in men which probably happens due to improved glucose metabolism and decreased plasma concentration of insulin.
Coffee constituents also work as antioxidants, thus engulfing the abnormal or mutant cells being formed in the beginning of the localized prostate cancer. It has anti-inflammatory properties which can indirectly regulate the levels of sex hormones in man and play a role in decreasing the risk of prostate cancer development in near future.
This study suggests that increased coffee consumption may be associated with a reduced risk of prostate cancer because of the decreased levels of blood glucose and the possible degradation of chlorogenic acid and similar products in the body increase the sensitivity of insulin in the body. In short, an improved body metabolism is the factor that causes prostate cancer prevention.
However, further research is still recommended to explore the underlying mechanisms and active compounds in coffee so as to better the public health policies dealing with men’s health.